In this episode, we dive deep into Ankylosing Spondylitis (AS), a chronic inflammatory condition also known as axial spondylarthropathy. We discuss key topics like the HLA-B27 marker, common symptoms such as spine stiffness and lower back pain, and potential complications like spinal fusion and anterior uveitis. Learn about diagnostic methods, including the Schober’s test, and imaging techniques like X-rays and MRI for early detection. We also explore AS treatments, from NSAIDs and physical therapy to advanced biologic therapies (TNF-alpha inhibitors, IL-17 inhibitors). This is a medical education episode for healthcare professionals.