More than two-hundred and thirty-million Americans have a Mastercard in their wallets. That number nearly triples outside U-S borders. There are more than six-hundred-million cardholders worldwide. This is part of Mastercard’s larger push for financial inclusion among underserved populations. As the company’s global efforts have grown, so has its focus on the global economy. In June, Executive Vice Chairman Ann Cairns, joined Fortune’s Most Powerful Women Summit in London.