Code3Club

Antabuse / Disulfiram


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Antabuse / Disulfiram

 

Drug Class: Alcohol Antagonist / Psychiatric medication

MOA: Inhibits acetaldehyde dehydrogenase from breaking down alcohol into acetic acid.

Indications: Individuals who desire to quit alcohol consumption and have an addiction

Contraindications: Sensitivity or adverse reaction to prior use of Antabuse

Interactions: Cough syrups or alcohol containing products, some blood thinners

Side effects: headache, breathing problems, nausea, vomiting, dizziness, extreme tiredness, fainting, fast/irregular heartbeat, or blurred vision. These symptoms can last from 30 minutes to several hours.

Precautions: thiuram or thiuram-related chemicals (found in pesticides and rubber), mouthwash, aftershave, sauces, vinegars) while taking this medication and for 2 weeks after stopping the medication

Routes of administration: oral

Onset of action: 10 minutes

Dosage: 250mg – 500mg daily

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