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For most of the last century, apigenin was a footnote — a yellow pigment in chamomile and parsley, studied mostly by people cataloguing the antioxidants in plants. In the last few years it has become one of the most-recommended compounds on the internet: the third ingredient in the famous sleep stack, a fixture in longevity protocols built around NAD+, and an addition to formulas aimed at cellular aging itself. But how does the evidence hold up?
0:00 - Introduction
0:45 - Why apigenin is everywhere right now
2:30 - How apigenin works
4:30 - Human anxiety trials
6:00 - Second discovery
8:00 - What the marketing gets wrong
10:45 - Where the evidence actually stands
12:20 - Should you take it?
By William Wallace, Ph.D.
For most of the last century, apigenin was a footnote — a yellow pigment in chamomile and parsley, studied mostly by people cataloguing the antioxidants in plants. In the last few years it has become one of the most-recommended compounds on the internet: the third ingredient in the famous sleep stack, a fixture in longevity protocols built around NAD+, and an addition to formulas aimed at cellular aging itself. But how does the evidence hold up?
0:00 - Introduction
0:45 - Why apigenin is everywhere right now
2:30 - How apigenin works
4:30 - Human anxiety trials
6:00 - Second discovery
8:00 - What the marketing gets wrong
10:45 - Where the evidence actually stands
12:20 - Should you take it?