With global business, there is an ever-growing need to be able to implement multi-region active-active architecture. However, this requires first-order thinking and attention not just to app and database design but also to DNS, monitoring, traffic shaping, and so on. Furthermore, architecture complexity can increase rapidly, so multiple design trade-offs need to be made. In this session, we discuss challenges and solutions using various AWS services, like Amazon DynamoDB global tables, as well as open source products.