"The Scream" by Edvard Munch is a renowned painting depicting a figure experiencing intense existential anxiety. The painting's swirling lines, distorted forms, and vibrant color palette evoke feelings of isolation and turmoil, reflecting Munch's own psychological struggles. It is a testament to the anxieties of late 19th and early 20th century Europe, mirroring the rise of existentialism and introspective exploration of the subconscious. "The Scream" has become a cultural icon, representing the universal experience of feeling overwhelmed and alienated in a seemingly indifferent world.