BioBits & Bytes

Artificially Expanded Genetic Information Systems (AEGIS): Redefining the Language of Life


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In this episode of Beyond ATCG, we explore the frontier of synthetic genetics through Artificially Expanded Genetic Information Systems (AEGIS). While nature relies on four nucleotides — A, T, C, and G — scientists have engineered new, non-natural base pairs that dramatically expand DNA’s coding potential. Discover how AEGIS enables the creation of unnatural DNA with increased information density, enhanced molecular recognition, and new biological functions.
We’ll dive into real-world applications in molecular diagnostics, nanotechnology, drug development, and even astrobiology — where synthetic bases might help us search for life beyond Earth.
This episode is for anyone fascinated by the reprogramming of life’s blueprint.
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BioBits & BytesBy Arghya Ghosh