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Acetylsalicylic Acid
Trade NameAspirin
IndicationRheumatoid arthritis, osteoarthritis, ischemic stroke, and MI prophylaxis
ActionInhibits the production of prostaglandins which leads to a reduction of fever and inflammation, decreases platelet aggregation leading to a decrease in ischemic diseases
Therapeutic ClassAntipyretics, non-opioid analgesics
Pharmacologic ClassSalicylates
Nursing Considerations• Use caution in bleeding disorders, chronic alcohol use • May lead to Stevens-Johnson syndrome, laryngeal edema, and anaphylaxis • Increases risk for bleeding with warfarin, heparin, and clopidogrel • Increased risk for GI bleeding with NSAID use • Monitor liver function tests • Concurrent use with alcohol may increase risk for GI bleeding • Aspirin with viral infections can cause Reye’s syndrome
By Jon Haws, RN CCRN Alumnus4.4
157157 ratings
Acetylsalicylic Acid
Trade NameAspirin
IndicationRheumatoid arthritis, osteoarthritis, ischemic stroke, and MI prophylaxis
ActionInhibits the production of prostaglandins which leads to a reduction of fever and inflammation, decreases platelet aggregation leading to a decrease in ischemic diseases
Therapeutic ClassAntipyretics, non-opioid analgesics
Pharmacologic ClassSalicylates
Nursing Considerations• Use caution in bleeding disorders, chronic alcohol use • May lead to Stevens-Johnson syndrome, laryngeal edema, and anaphylaxis • Increases risk for bleeding with warfarin, heparin, and clopidogrel • Increased risk for GI bleeding with NSAID use • Monitor liver function tests • Concurrent use with alcohol may increase risk for GI bleeding • Aspirin with viral infections can cause Reye’s syndrome

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