
Sign up to save your podcasts
Or


How NanoKnife differs from thermal ablation techniques
Dr. Brent Sharpe of Northside Hospital Forsyth in Cumming, GA
How does NanoKnife (irreversible electroporation) truly differ from traditional thermal ablation techniques like cryotherapy, radiofrequency ablation (RFA), and microwave ablation? In this in-depth educational discussion, Vic Senese, RN, BSN, FAUNA, host of UroNurse, is joined by Dr. Brent Sharpe, urologist at Northside Hospital Forsyth in Cumming, Georgia, to break it all down.
This episode explores how NanoKnife uses high-voltage electrical pulses instead of heat or cold to destroy targeted cancer cells while preserving surrounding structures such as nerves, blood vessels, and the urethra. Unlike thermal ablation, which relies on extreme temperatures and can cause collateral tissue damage, NanoKnife offers a non-thermal, precision-based approach that is increasingly being discussed in focal therapy for prostate and other solid tumors.
Dr. Sharpe explains:
The science behind irreversible electroporation
Key differences between NanoKnife and thermal ablation
Why tissue preservation matters in urologic cancer care
Potential benefits and limitations of NanoKnife technology
Patient selection considerations and real-world clinical insights
Whether you’re a healthcare professional, urology nurse, medical student, or a patient seeking to understand emerging cancer treatment options, this conversation delivers clear, practical explanations without the hype.
👉 Subscribe to the UroNurse channel for expert-led discussions on urology, cancer care, and advanced medical technologies:
https://www.youtube.com/@UroNurse1
The expert's opinions in this communication are personal and not representative of any organization. They are for informational purposes only, not official guidance. Viewers are advised to use their judgment, seek additional advice, and take responsibility for any actions based on these opinions.
By UroNurse5
66 ratings
How NanoKnife differs from thermal ablation techniques
Dr. Brent Sharpe of Northside Hospital Forsyth in Cumming, GA
How does NanoKnife (irreversible electroporation) truly differ from traditional thermal ablation techniques like cryotherapy, radiofrequency ablation (RFA), and microwave ablation? In this in-depth educational discussion, Vic Senese, RN, BSN, FAUNA, host of UroNurse, is joined by Dr. Brent Sharpe, urologist at Northside Hospital Forsyth in Cumming, Georgia, to break it all down.
This episode explores how NanoKnife uses high-voltage electrical pulses instead of heat or cold to destroy targeted cancer cells while preserving surrounding structures such as nerves, blood vessels, and the urethra. Unlike thermal ablation, which relies on extreme temperatures and can cause collateral tissue damage, NanoKnife offers a non-thermal, precision-based approach that is increasingly being discussed in focal therapy for prostate and other solid tumors.
Dr. Sharpe explains:
The science behind irreversible electroporation
Key differences between NanoKnife and thermal ablation
Why tissue preservation matters in urologic cancer care
Potential benefits and limitations of NanoKnife technology
Patient selection considerations and real-world clinical insights
Whether you’re a healthcare professional, urology nurse, medical student, or a patient seeking to understand emerging cancer treatment options, this conversation delivers clear, practical explanations without the hype.
👉 Subscribe to the UroNurse channel for expert-led discussions on urology, cancer care, and advanced medical technologies:
https://www.youtube.com/@UroNurse1
The expert's opinions in this communication are personal and not representative of any organization. They are for informational purposes only, not official guidance. Viewers are advised to use their judgment, seek additional advice, and take responsibility for any actions based on these opinions.