How drug treatment may be able to help the body’s own immune system to defeat cancerous tumors, with Ira Mellman (0:00) (Immunity special issue on cancer immunotherapy). How improved understanding of the immune system's reaction to food would help reduce the epidemic of food allergies, with Hugh Sampson (13:45) (Trends in Immunology). Plus, sample a selection of the hottest new papers from Cell Press (25:27).