In The Mix

Avoid the VPD Death Spiral


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When you’re cultivating in a sealed environment like a grow room or a grow tent, running high CO₂ without enough humidity can trigger what Tyler calls the VPD Death Spiral — a feedback loop where humidity drops, stomata close, and growth grinds to a halt.

This episode breaks down:

  • Why high CO₂ lowers stomatal conductance
  • How sealed rooms create extreme VPD conditions
  • How to fix it fast with humidifiers or light adjustments
  • Why overusing CO₂ can reduce productivity

If you’ve ever seen plants stop transpiring in a sealed setup, this one’s for you.

00:00 – The VPD Death Spiral Explained00:38 – Why CO₂ Makes It Worse01:15 – The Feedback Loop in Sealed Rooms02:00 – How to Fix It (Humidifiers & Light Control)03:00 – Real-World Examples

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In The MixBy Front Row Ag