Messy Minded Podcast

Axolotl


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In this episode of Messy Minded, Jess explores the axolotl — the permanently aquatic salamander that refuses to grow up. Through biology, mythology, and modern science, we unpack how axolotls regrow limbs, spinal cords, and even parts of their brains, and why researchers studying regeneration and immune response are obsessed with them

The episode weaves together Aztec mythology and the god Xolotl, neoteny, and the misunderstood “smile”. We also confront the collapse of wild axolotl populations in Lake Xochimilco, conservation efforts, and why one of the most studied animals on Earth is critically endangered in its natural habitat.

Funny, dark, science-forward, and unexpectedly philosophical, this episode asks what it means to stay in a liminal state — and whether sometimes the smartest move isn’t to transform at all.


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https://open.spotify.com/show/3htrTJx4ORepBRYxJ7ZGPv?si=0f78e1cd20114a98

https://podcasts.apple.com/us/podcast/messy-minded-podcast/id1819603605


A foundational overview of axolotl regeneration can be found in “Regeneration in the Axolotl: A Model for Mammalian Wound Healing” published in Nature Reviews Molecular Cell Biology. Other sources for this episode were a 2018 paper “The Axolotl Genome and the Evolution of Key Tissue Formation Regulators” in Nature, work by James Godwin and colleagues, particularly “Macrophages Are Required for Adult Salamander Limb Regeneration” published in Proceedings of the National Academy of Sciences (PNAS), The Journal of Experimental Biology and Integrative Zoology,and Biological Conservation. Myth largely from various internet searches and “Aztec Mythology: A Guide to the Gods, Heroes, Rituals, and Beliefs of the Aztecs” by David Carrasco and “The Gods and Symbols of Ancient Mexico and the Maya” by Mary Miller and Karl Taube. 


Music by: SoundPlusUS Label and Mr. Lex Oleksii Bezalov for "Spark Groove", Nikita Kondrashev for "Cosy, Quirky, Comedy", "Quirky sneaky memes background music" by Mykola Odnoroh, "Bass Stories" by Unknown Artist, "Latin Mexican Latino Music" by HitsLab and Levgen Poltavsky, "On TipToe" by Geoff Harvey

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Messy Minded PodcastBy Messy Minded