Scope Shift

Being a Serial Entrepreneur in the Digital Space Ep20


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In this episode of the Scope Shift Podcast, host Brian Saemann sits down with Lysa Miller, Founder of Ladybugz Interactive, a boutique web and digital growth agency specializing in early-growth biotech, nonprofit, and women-owned businesses. Lysa is not just an agency leader—she’s a serial entrepreneur who has launched agencies, built startup communities, and created coworking spaces. Her journey is a powerful example of resilience, reinvention, and building businesses with purpose.


🎯 What You'll Learn:

✅ How Ladybugz Interactive evolved to serve biotech, nonprofit, and service-based clients.

✅ Why Lysa launched a dedicated biotech agency to meet unique client needs.

✅ The “brand accelerator” model and why early investment in brand and messaging pays off.

✅ How to position an agency for long-term partnerships rather than one-off projects.

✅ Building agile teams, flexible packages, and pricing models tailored to client growth stages.

✅ Lysa’s philosophy on balancing profit with culture—including her 32-hour work week model.

✅ Why creating separate niche agencies can actually be more efficient than one large agency.

✅ The impact of COVID-19 on boutique agencies and why being small and agile was an advantage.

✅ Lysa’s honest take on entrepreneurship at 50+ and why it’s never too late to start.

✅ The mindset shift from “this is my business” to “this is our gift,” empowering teams to thrive.


🧠 Guest Spotlight: Lysa Miller – Founder & CEO of Ladybugz Interactive Lysa is a bold, creative leader with deep experience in digital strategy, community building, and entrepreneurship. She helps early-growth companies build strong brands, powerful websites, and sustainable marketing foundations—all while redefining what it means to run a modern digital agency.


🔗 Connect with Lysa:

  • Website: ladybugsz.com

  • LinkedIn: Lysa Miller

🔍 Topics Covered:

  • From freelancer to agency founder: Lysa’s iterative journey in digital.

  • Why boutique agencies have an edge in tough economic times.

  • The challenges and opportunities of serving biotech companies.

  • Client education: teaching startups why brand and messaging matter.

  • Structuring agencies with future sales and exits in mind.

  • Building culture with flexibility, trust, and work-life balance.

  • Why purpose-driven entrepreneurship leads to stronger client partnerships.

  • How to stay open to reinvention at every stage of your journey.

📌 Resources & Links:

  • GoBeyond SEO Digital Marketing: gobeyondseo.com

  • Transform your revenue generation with GoBeyond Data: gobeyondseo.com/daas

  • Get a free Google Maps Audit with Archer: audit.archer.gobeyondseo.com

  • Connect with Brian here: Brian Saemann on LinkedIn

👍 Like, comment, and subscribe for more expert insights on agency life, digital marketing, and entrepreneurial growth.

#Entrepreneurship #DigitalAgency #BiotechMarketing #WomenInBusiness #StartupGrowth #LadybugzInteractive #LysaMiller #AgencyLife #BrandStrategy #ScopeShiftPodcast

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Scope ShiftBy Brian Saemann