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Ben Roethlisberger is done for the season (maybe forever?), and Drew Brees is down for a while. What does that mean for the fantasy factors remaining in their offenses? Plus, who should you be targeting on waivers this week after the RB injuries and another week of impressive rookie wideouts?

Here's the rundown:

Ben Roethlisberger out, Mason Rudolph in ... 1:04

Drew Brees opens door for Teddy Bridgewater ... 8:00

Other injuries to monitor ... 12:39

Sorting the backfields ... 18:45

Re-visiting the Week 1 WR breakouts ... 30:37

Streaming D picks ... 40:53

​Check out our Week 3 Free Agent Focus for bid recommendations on all of this week's waiver targets. And take a look at our updated Rest of the Way rankings.

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