Better Off Daily-13— GLP-1s + Hormones: The Combo That Changes Everything

New research confirms what we've been doing in the clinic for years: hormone optimization alongside GLP-1 therapy produces meaningfully better weight loss outcomes. Here's what the data shows — and what it means for your protocol.

Research referenced in this episode:

• Castaneda R, et al. Tirzepatide + hormone therapy in postmenopausal women — presented at The Menopause Society 2025 Annual Meeting. Coverage: https://www.ajmc.com/view/tirzepatide-plus-hormone-therapy-boosts-weight-loss-in-menopause-regina-castaneda-md
• Lancet Obstetrics coverage of the same findings: https://www.sciencealert.com/unexpected-drug-combo-may-supercharge-weight-loss-in-older-women
• GLP-1 medications and testosterone recovery in men — presented at ENDO 2025, Endocrine Society Annual Meeting. Coverage: https://austinthyroid.com/how-glp-1-medications-may-boost-testosterone-naturally

Go deeper: 📖 Better Off: The GLP-1 Protocol 📖 Better Off: Weight Loss 📋 Free Guide 🛒 Better Off Protein 📱 @betteroffwellness on Instagram and TikTok

I'm a nurse practitioner, I own a weight loss clinic, and this is education — not medical advice. Nothing here replaces a conversation with your own provider.