In this episode of the Buffalonian podcast, Joe Cali and Dom Loss discuss the upcoming matchup between the Buffalo Bills and the New England Patriots. They reflect on the Bills' unexpected success this season and their offensive strategies. They analyze the defensive matchups, injury updates, and the implications for the playoff picture, emphasizing the importance of securing the number one seed. The conversation also touches on their fantasy football championship matchup, highlighting the competitive nature of their league.

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