This episode focuses on long-term mechanical circulatory support and how durable LVAD therapy is shaping contemporary heart failure management. Joined by Gloria Färber and Daniel Zimpfer, we discuss key advances in device technology, the ongoing challenge of driveline complications, and the critical question of patient selection and timing. The conversation explores LVADs as destination therapy or bridge to transplant, managing right ventricular failure, and the role of temporary support. Looking ahead, the episode highlights emerging technologies and why mechanical circulatory support will remain central to advanced cardiac surgery.