What if nirvana isn't a mystical fantasy, but a biological state triggered by forcing our brains to abandon their energy-saving shortcuts? This episode investigates the "predictive brain" — the evolutionary mechanism that shows us an approximation of reality to save calories. We then journey through history, examining the lives of figures like the Buddha, Rumi, and Teresa of Ávila, to see if their "illuminated" states were the result of overriding this predictive process for a direct, unfiltered experience of the world.