Columbia University BioWorks

BioWorks 26: Building Organoids Models and Active Learning Algorithms with Arvind Thiagarajan


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In which Arvind Thiagarajan, Co-founder and CTO of Tessel Biosciences, shares how he is combining organoid models with active learning algorithms to generate clinically-relevant data with greater experimental efficiency to ultimately develop novel therapeutics. He also discusses how his prior experiences at MIT, D.E Shaw, BenevolentAI, and Verily each shaped his career and worldview into the engineer and founder he is today.

Hosted by Kevin Xu.


Timestamps:

(00:00) Intro

(05:30) Takeaways from DESRES, BenevolentAI, and Verily

(15:57) Speed, cost, and success rate trends in drug development

(33:37) Core research workflow of Tessel Bio

(44:09) Tesselogic and active learning

(47:01) Coordinating wet-lab and dry-lab innovations

(50:19) Advice for aspiring scientist-founders


Links:

Tessel Biosciences - https://tessel.bio/

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Columbia University BioWorksBy Columbia University Systems Biology Initiative