Vidcast:  https://youtu.be/ezZII2jLS2c

 

zaaThose taking anti-hypertensive drugs that cross the blood-brain barrier showed better memory function compared with those on blood pressure medications that cannot cross that barrier.  Neuroscientists at UC-Irvine now publish their meta-analysis of 14 global studies covering nearly 13,000 adults.

 

Those taking drugs in the ACE inhibitor or the ARB categories showed better memory recall during a 3 year followup period than those taking other blood pressure control medications.  ACE inhibitors included captopril, fosinopril, lisinopril, perindopril, ramipril, and trandolapril.  ARB drugs were telmisartan and candesartan.

 

These observations suggest that drugs capable of modulating angiotensin and crossing the blood-brain barrier may slow cognitive deterioration and dementia.

 

https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.121.17049

 

#dementia #antihypertensives #angiotensin #aceinhibitor #arb #bloodbrainbarrier