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On this one, Tyrone and I get into what we mean when we talk about odds and probability. Most people speak sloppily about these kinds of concepts, and it leads to people thinking sloppily about them. The conversation is kicked off by referencing this Haman Nature article.

Want to really understand the difference between “odds” or “probability” and “my best guess is…”? Ask a professional gambler!

Plus, we get into simulation theory, Drake’s equation, God, space aliens, crappy “science”, and the wonderful Michael Crichton.