This episode unpacks Canada's National Security Guidelines for Research Partnerships (NSGRP), a framework designed to protect Canadian research from foreign interference, espionage, and unwanted knowledge transfer. We explore the guiding principles of these guidelines—balancing the need for research to be "as open as possible and as secure as necessary"—and discuss what researchers need to consider about sensitive research areas and potential partners. Tune in to understand how Canada is safeguarding its innovation ecosystem while maintaining a commitment to open and collaborative research