This release contains only the music track from Base by Base Episode 388.

Song title: Borrowed Time, Brand-New Liver
Original Base by Base episode: 388: Base by Base | Episode 388 — In situ CAR‑macrophage alleviates liver fibrosis

Article metadata:
Article title: mRNA‑laden LNP‑enabled in situ CAR‑macrophage alleviates liver fibrosis via inhibiting activated HSCs and modulating the immune microenvironment
Journal: Proceedings of the National Academy of Sciences (PNAS)
DOI: 10.1073/pnas.2534673123
Reference: Huang X, Wang J, Hao J, et al. mRNA‑laden LNP‑enabled in situ CAR‑macrophage alleviates liver fibrosis via inhibiting activated HSCs and modulating the immune microenvironment. Proc. Natl. Acad. Sci. U.S.A. 2026;123(22):e2534673123. doi:10.1073/pnas.2534673123. Published May 29, 2026.

Lyrics:
Verse 1
In the dim-lit lab where the red lines grow,
Scar tissue stacking like a heavy shadow.
But a tiny message rides a lipid glow,
Knocking on the cells that started the battle.

Pre-Chorus
Find the marker, hit the right door,
Turn the hunters into healers once more.
Not forever—just enough to change the score,
A spark in the dark on the cellular floor.

Chorus
Send the mRNA, let it light the switch,
Teach the macrophage to lock onto the itch.
Clear the FAP signal, cut the tethered pain,
Break down the walls, let the blood run clean again.
We don’t need forever, we just need right now—
Watch the scar unwind, watch the body remember how.

Verse 2
It’s a quick-lived badge on an immune-cell frame,
A focused grip, not a runaway flame.
Phagocytosis rising like a drumline beat,
Old collagen crumbling under moving feet.

Bridge
Syk to the signal, NF-kappa to the roar,
Matrix starts to loosen where it locked before.
MMP12 humming through the crowded space,
And the tissue turns—slowly—toward a gentler place.

Final Chorus
Send the mRNA, let it light the switch,
Teach the macrophage to lock onto the itch.
Clear the FAP signal, cut the tethered pain,
Break down the walls, let the blood run clean again.
Transient and targeted—yeah, that’s the vow—
Watch the scar unwind, watch the body remember how.