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🧬 Podcast Summary: “Genetics, CRISPR, and Bio-Upgrades from Old Science”
By the Mad Scientist Supreme


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🧠 Genetics and Body Weight – Gattaca, Here We Come

📅 From Science Magazine, July 2021: Large-scale genetic studies have confirmed that body weight is at least partly genetic. By analyzing gene databases across thousands of individuals, researchers identified specific genes that influence weight.

🧪 The Mad Scientist Supreme draws a sharp comparison to Gattaca, the dystopian sci-fi film where genetic screening dictates social status and employment. While genetic discrimination is technically illegal in the U.S., the podcast warns that legal protections are not always enforced—suggesting that screening for weight-prone genes may still quietly shape real-world decisions.


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🔬 CRISPR Inside the Body – Editing From Within

📍 Science Magazine, July 2021, page 70: A CRISPR gene-editing treatment was injected directly into a patient’s bloodstream for the first time to correct a genetic liver disease.

💡 While this case only deactivated a harmful immune gene in the liver, it signals a major shift: gene editing isn’t just happening in labs anymore—it’s moving into the body.

🧬 The Mad Scientist Supreme sees this as the first step in a broader revolution: not just eliminating disease, but enhancing humanity.


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🐴 The Mule and the Toxin – A Forgotten Military Experiment

📖 A curious wartime anecdote: During WWII, a plan to assassinate a Japanese general using purified botulism toxin failed when a cautious intermediary tested the poison on a mule—which survived. That led to the mission being aborted.

💡 Turns out, mules are resistant to botulism due to a unique liver response. The takeaway?
If we can CRISPR-edit human genes, we could theoretically borrow this trait from mules, making ourselves resistant to such toxins.

⚠️ Is botulism exposure likely? No.
📈 Is the upgrade worthwhile? Maybe.
🧠 But symbolically, it shows the potential for “small but significant” human enhancements.


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🧵 Final Threads

Page 73 of the same Science issue holds a detailed analysis on gene-weight correlations.

A short mention of direct optical polymer patterning (page 16) for materials scientists interested in controlling polymers with lasers—an unexpected side note for future tech applications.



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👨‍🔬 Conclusion
This episode blends history, cutting-edge genetics, and philosophical warning: CRISPR is no longer theoretical, and while its medical use is just beginning, the door to human enhancement is now open. Whether we use it to eliminate disease—or to become something more—is no longer science fiction.

🔍 Stay tuned for more discoveries as the Mad Scientist Supreme continues digging through old articles and new ideas.

Botox and body weight