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Summary:  This episode is about taking a toxin, isolating it, purifying it and then injecting it into your face; or other parts of your body.  Safe use of botulism toxin A relies upon its local activity.  The indications include cosmetic smoothing, excessive sweating, eye disorders, chronic migraines, and overactive bladder.  Assessing the Benefit-Risk of Botox is also discussed, along with the need for close monitoring.

Topics:

·       Botulism Toxin A 01:30

·       Premarin 02:15

·       Exotoxin & Endotoxin 03:00

·       Biological Warfare 03:30

·       Indications

-              Cosmetic

-              Severe Sweating

-              Cervical Dystonia

-              Blepharospasm

-              Strabismus

-              Chronic Migraine

-              Overactive Bladder

·       History of Botox 05:50

·       Mechanism of Action 06:20

·       Benefit-Risk 08:30

·       Local Effect 10:30

·       Side Effect Rare 13:00

·       Iatrogenic Bolulism

·       Monitor – Journal 13:30

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