Dr. Howard Smith Reports

Bottlebrush-shaped Nanoparticle Delivers Complex Cancer Chemotherapy


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Vidcast: https://youtu.be/7P4GJ-yNLMc

As precision oncologic therapy advances, we are learning that many cancers respond only to a combination of chemotherapeutic agents. MIT, Harvard, and Dana-Farber Cancer Institute investigators in collaboration with the MIT spinoffs Ceptur Therapeutics and Window Therapeutics have developed unique nanoparticles shaped like bottle-brushes. These carrier molecules capably transport multiple chemotherapeutic agents to and into cancer cells. Studies are underway to use this unique transport mechanism to also carry mRNA and therapeutic antibodies.

https://www.nature.com/articles/s41565-022-01310-1

#chemotherapy #cancer #nanomolecules #precisiononcology #mRNA #antibodies


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Dr. Howard Smith ReportsBy Howard G. Smith MD, AM