Health Facts

Breakdown of Kreb's Cycle (Guided Approach)


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Now, let's break down the Krebs cycle into its key stages and highlight the main reactions that take place:

  1. Acetyl-CoA Formation:

  2. The cycle begins when a two-carbon molecule called acetyl-CoA combines with a four-carbon molecule called oxaloacetate, forming a six-carbon molecule known as citrate. This step is catalyzed by the enzyme citrate synthase.

  3. Citrate Isomerization:

  4. The citrate molecule then undergoes a series of rearrangements, resulting in its isomerization into isocitrate. This conversion is facilitated by the enzyme aconitase.

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    Health FactsBy Mike Colella

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