Penn Medicine is a $4.3 billion health care provider organization consisting of over 2,000 physicians providing services to the Hospital of the University of Pennsylvania, Penn Presbyterian Medical Center, Pennsylvania Hospital, Chester County Hospital, Lancaster General Health System and the health system network that serves the city of Philadelphia, the surrounding five county area and parts of southern New Jersey. At the annual Oracle Industry Connect conference, Brian Wells discusses how informatics can help the assist the physician in clinical decision support at Penn Medicine.