In this episode of No Brain Behind, Dr. Virginia Howard (University of Alabama at Birmingham) and Dr. Matt Reeves (Michigan State University) discuss disparities in stroke care and research for women. They examine women-specific risk factors, the development of stroke risk scores, and barriers to women’s participation in clinical trials, along with emerging strategies to address these gaps. The conversation also highlights the work of PROWESS, an international initiative advancing research in women’s stroke care, and offers insights into future directions in stroke and women’s health research.