Infection Control Matters

Brush, Rinse, Prevent: The HAPPEN Trial Story


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The tables are turned in this episode. Prof Trisha Peel and Dr Sally Havers guest host this podcast and interview Brett Mitchell, Nicole White and Martin Kiernan about their recent publication in Lancet Infectious Disease.


The publication showcases results from a recent multi-centre RCT demonstrating the benefit of improving oral care in reducing the risk of non-ventilator associated pneumonia (NV-HAP). The authors are probed about why they did the study, key findings, implementation and other aspects not always published in peer reviewed journals.

White NM, Russo PL, Matterson G, Browne K, Cheng AC, Kiernan M, et al. Effectiveness of oral care for the prevention of non-ventilator hospital-acquired pneumonia (HAPPEN): a multicentre, stepped-wedge, cluster-randomised trial in Australia. Lancet Infect Dis 2026. https://doi.org/10.1016/S1473-3099(26)00235-5

Information about the study available here: https://happenstudy.com/

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Infection Control MattersBy Brett Mitchell

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