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Bupropion
Trade NameWellbutrin
IndicationDepression, smoking cessation, treat ADHD in adults
ActionNot well understood, ↑ dopaminergic and noradrenergic transmission via reuptake
Therapeutic ClassAntidepressants, smoking deterrents
Pharmacologic ClassAminoketones
Nursing Considerations• May lead to seizures, suicidal thoughts • Do not administer if patient is taking MAOI • Use caution with renal and liver impairment • Assess mental status • Instruct patient to avoid alcohol (may lead to hallucinations, seizures, anxiety)
By Jon Haws, RN CCRN Alumnus4.4
158158 ratings
Bupropion
Trade NameWellbutrin
IndicationDepression, smoking cessation, treat ADHD in adults
ActionNot well understood, ↑ dopaminergic and noradrenergic transmission via reuptake
Therapeutic ClassAntidepressants, smoking deterrents
Pharmacologic ClassAminoketones
Nursing Considerations• May lead to seizures, suicidal thoughts • Do not administer if patient is taking MAOI • Use caution with renal and liver impairment • Assess mental status • Instruct patient to avoid alcohol (may lead to hallucinations, seizures, anxiety)

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