Welcome to KDIGO Conversations in Nephrology: Burden and Pathophysiology of APOL1 Kidney Disease! Join our host Dr. Kirk Campbell (University of Pennsylvania) as he speaks with Dr. Bessie Young (University of Washington) about the discovery, impact, and future of APOL1 kidney disease.

This episode explores the significant burden of kidney disease driven by APOL1 gene variants in individuals with African ancestry. You’ll learn about the history of the gene's discovery and its association with kidney conditions like FSGS.

Dr. Young explains the complex pathophysiology of APOL1 and highlights the speed of research, new findings like a protective APOL1 variant, and ongoing clinical trials for novel treatments.

This series is provided by KDIGO and supported by Vertex.