Burnout, compassion fatigue, and caregiver strain are related concepts stemming from prolonged stress and caregiving responsibilities. Burnout involves overall exhaustion from overwork and stress. Compassion fatigue is specific to caregivers and healthcare workers, leading to emotional numbness due to witnessing suffering. Caregiver strain encompasses the physical, emotional, and financial challenges caregivers face. All three require self-care and support to maintain well-being.