Get ready for DNA mutation rates across the generations, a potential Alzheimer’s ‘vaccine’, tissue-expansion mass-spectrometry, updating old methods in SAS, planning a statistical analysis, and seven new Cancer Grand Challenges. Science On.

References:

• Human de novo mutation rates from a four-generation pedigree reference
• Targeting of phosphorylated tau at threonine 181 by a Qβ virus-like particle vaccine is safe, highly immunogenic, and reduces disease severity in mice and rhesus macaques
• TEMI: tissue-expansion mass-spectrometry imaging
• Updating old SAS programs: A case study with PROC LOESS
• Strategies for Choosing and Planning a Statistical Analysis
• USAMRAA: Alzheimer’s Research Program Transforming Research Award
• Cancer Grand Challenges

R Packages:

• circlizePlus: Using 'ggplot2' Feature to Write Readable R Code for Circular Visualization
• glmfitmiss: Fitting GLMs with Missing Data in Both Responses and Covariates