The New Orleans Saints play the San Francisco 49ers in Week 2 of the NFL season on Sunday. The Niners likely will be without starting quarterback Brock Purdy and tight end George Kittle, so it's an opportunity for Saints coach Kellen Moore and quarterback Spencer Rattler to notch their first victories. We break down the matchups on both sides of the ball, give injury updates and let you know the inside scoop from the locker room. Finally, we give you keys to the game and score predictions for Saints-49ers. #saints #neworleanssaints #whodat #whodatnation #nfl #nflweek2 #football #footballpicks #fantasyfootball