The medication Viagra has been shown to have positive impact on the heart in recent research. Host Dr. Larry Kaskel discusses with Dr. David Kass, the Abraham and Virginia Weiss Professor of Cardiology and professor of biomedical engineering at Johns Hopkins University, the history of Viagra as a medicine developed for the heart. Dr. David Kass explains the results of his research with mice and how sildenafil triggers an important heart protein, RGS2, and why this enzyme may prevent heart failure. Tune in to hear the next chapter of Viagra as a shield against high blood pressure damage and its potential for future cardiovascular protective effects.