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Generic Name

Captopril

Trade Name

Capoten

Indication

Hypertension, management of CHF, decrease progression of DM neuropathy

Action

Block conversion of angiotensin I to angiotensin II, increases renin levels and decreases aldosterone leading to vasodilation

Therapeutic Class

Antihypertensives

Pharmacologic Class

ACE Inhibitor

Nursing Considerations

• Can cause neutropenia – check WBCs regularly • Use cautiously with potassium supplements and potassium sparing diuretics • Use cautiously with diuretic therapy • Administer 1 hour before meals • Monitor blood pressure often • Monitor weight and fluid status • Monitor renal profile • Monitor CBC frequently • May lead to Rhabdomyolysis • Dry cough