The Week 6 showdown is here! Marcus breaks down the Arizona Cardinals’ run-heavy offense, their revamped 3–4 defense, and how they match up against a balanced Indianapolis Colts squad led by Jonathan Taylor and Daniel Jones. We cover key injuries, matchup X-factors, and what each team needs to do to grab a crucial midseason win. Tune in for analysis, predictions, and everything you need before kickoff!

Learn more about your ad choices. Visit megaphone.fm/adchoices