The Critical Care Practitioner

CCP Podcast 094: Magnesium for the win.


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"Magnesium For the Win!"- with Bryan Boling. Guest: Habib Srour Dr. Srour is an attending in the Anesthesia Critical Care Division at the University of Kentucky where I practice. The episode is the first in a mini-series on electrolyte imbalances in the ICU. I hope to record an episode on hyponatremia soon. In the episode, we talk about a few studies that I said we'd link in the show notes: Review: Fawcett WJ, Haxby EJ, DaleDA. Magnesium: physiology and pharmacology. Br J Anaesth. 1999 Aug;83(2):302-20 https://www.ncbi.nlm.nih.gov/pubmed/10618948 Neuro: Bhudia SK, Cosgrove DM, Naugle RI, Rajeswaran J, Lam BK, Walton E, et al. Magnesium as a neuroprotectant in cardiac surgery: a randomized clinical trial. J Thorac Cardiovasc Surg. 2006;131:853-61. https://www.ncbi.nlm.nih.gov/pubmed/16580444 Koinig H, Wallner T, Marhofer P, Andel H, Hörauf K, Mayer N. 1998. Magnesium sulfate reduces intra- and postoperative analgesic requirements. Anesth Analg. 1998 Jul;87(1):206-10. https://www.ncbi.nlm.nih.gov/pubmed/9661575 Cardiac: Speziale G, Ruvolo G, Fattouch K, et al. Arrhythmia prophylaxis after coronary artery bypass grafting: regimens of magnesium sulfate administration. Thorac Cardiovasc Surg 2000; 48: 22–6. https://www.ncbi.nlm.nih.gov/pubmed/10757152 Dorman BH, Sade RM, Burnette JS, et al. Magnesium supplementation in the prevention of arrhythmias in pediatric patients undergoing surgery for congenital heart defects. Am Heart J 2000; 139: 522–8. https://www.ncbi.nlm.nih.gov/pubmed/10689268 Minato N1, Katayama Y, Sakaguchi M, Itoh M. Perioperative coronary artery spasm in off-pump coronary artery bypass grafting and its possible relation with perioperative hypomagnesemia. Perioperative coronary artery spasm in off-pump coronary artery bypass grafting and its possible relation with perioperative hypomagnesemia. https://www.ncbi.nlm.nih.gov/pubmed/16572072 Pulmonary: Puri GD, et al. The Effect of Magnesium Sulphate on Hemodynamics and Its Efficacy in Attenuating the Response to Endotracheal Intubation in Patients with Coronary Artery Disease. Anesth Analg. 1998 Oct;87(4):808-11. https://www.ncbi.nlm.nih.gov/pubmed/9768774 Endocrine: Pasternak, et al. The effect of preoperative magnesium supplementation on blood catecholamine concentrations in patients undergoing CABG. Magnes Res. 2006 Jun;19(2):113-22 https://www.ncbi.nlm.nih.gov/pubmed/16955723

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The Critical Care PractitionerBy Jonathan Downham