New research shows that serotonin in the cerebellum plays a crucial role in regulating anxiety in mice. Higher cerebellar serotonin levels correlate with reduced anxiety-like behaviors, while lower levels increase anxiety. Scientists could bidirectionally control anxiety by manipulating cerebellar serotonin neurons, stimulating them to decrease anxiety and inhibiting them to increase it. This challenges prior assumptions about serotonin's role in anxiety and suggests potential new therapeutic targets for anxiety disorders. The findings will be published in the Journal of Neuroscience.

https://neurosciencenews.com/anxiety-serotonin-neuroscience-28410/

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