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Chiral Separation Methods for Pharmaceutical and Biotechnological Products
A comprehensive overview of chiral separation methods for pharmaceutical and biotechnological products, focusing on the critical issue of molecular handedness (chirality) in drug development. The text examines various chromatographic and electrophoretic techniques, including High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), Supercritical Fluid Chromatography (SFC), and Capillary Electrophoresis (CE), detailing their principles and applications for separating enantiomers. Furthermore, the sources discuss the regulatory considerations for chiral compounds from agencies like the FDA and EMEA, and explore the fundamental role of chirality in biomolecules and biotechnology products such as proteins. Finally, they cover high-throughput screening strategies and advanced topics like chiral sensors and the mechanisms of chiral discrimination using various stationary phases, such as modified cyclodextrins and polysaccharides.
You can listen and download our episodes for free on more than 10 different platforms:
https://linktr.ee/pharmacy_simple
Produced by:
https://www.podcaistudio.com/
You can listen and download our episodes for free on more than 10 different platforms:
https://linktr.ee/pharmacy_simple
Produced by:
https://www.podcaistudio.com/
View all episodes
By Pharmacy Made SimpleA comprehensive overview of chiral separation methods for pharmaceutical and biotechnological products, focusing on the critical issue of molecular handedness (chirality) in drug development. The text examines various chromatographic and electrophoretic techniques, including High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), Supercritical Fluid Chromatography (SFC), and Capillary Electrophoresis (CE), detailing their principles and applications for separating enantiomers. Furthermore, the sources discuss the regulatory considerations for chiral compounds from agencies like the FDA and EMEA, and explore the fundamental role of chirality in biomolecules and biotechnology products such as proteins. Finally, they cover high-throughput screening strategies and advanced topics like chiral sensors and the mechanisms of chiral discrimination using various stationary phases, such as modified cyclodextrins and polysaccharides.
You can listen and download our episodes for free on more than 10 different platforms:
https://linktr.ee/pharmacy_simple
Produced by:
https://www.podcaistudio.com/
You can listen and download our episodes for free on more than 10 different platforms:
https://linktr.ee/pharmacy_simple
Produced by:
https://www.podcaistudio.com/