Because individuals with high cholesterol levels often develop
heart disease, we've come to accept that high cholesterol -
especially "bad" cholesterol, or LDL - causes heart disease.
But it can't be said often enough that correlation does not
equal causation, and it is beginning to look more and more like a
causal realtionship between cholesterol and heart disease just
isn't there. 
In this episode we talk about the status of treating cholesterol
to prevent heart disease and about a drug trial that punctuates the
whole process with a giant question mark. 
Take a listen and see what you think.
Resources:

Number Needed to Treat with Statins for Primary Prevention

Number Needed to Treat with Statins for Secondary
Prevention

Evacitrapib Study Stopped Because of Clinical Futility

American Heart Association Guidelines for Prevention with
Statins

Ep 25: Cholesterol and Heart Disease: What We Don't Know

Join cohosts Kendall Britt, MD and Amy Rogers, MD for a 15 minute check-up on current issues in medicine and health policy. The doctors examine current medical concerns in light of the best available medical evidence and the policy issues of the day with a focus on their impact on the doctor patient relationship.

Medicine

Science & Medicine

Health & Fitness

There has been a lot of commentary in the news and in medical journals about the problem of maternal mortality - specifically how we are really crappy at tracking it, which makes it really difficult to know if interventions are working or making things worse. In a country with healthcare as advanced as it is in the U.S., this is just stupid. I mean, we could use fancier words, but the bottom line is stupid.   Today, 2 Docs Talk about maternal mortality, the problems with tracking it, and one place that's done a pretty good job of both tracking and improving the numbers.   Resources:   That Propublica article we kept referring to. Obstetrics and Gynecology article about trends and tracking  Identifying Maternal Deaths in Texas CMQCC Toolkits   WHO's Trends in Maternal Mortality

Episode 128: Tracking Maternal Mortality

Medicare can be confusing for a lot of folks. Part A, Part B, Part C, Part D – some are automatic, some require enrollment; some have premiums, some don't; some have eligibility requirements besides age, some don't. It can get confusing.   To try to take some of the mystery out of Medicare, today 2 Docs Talk about Medicare Part C, also known as Medicare Advantage Plans.  Take a listen and decide for yourself if these plans really offer any advantage.

Episode 127: Is There Really an Advantage to Medicare Part C?

Kratom doesn't sound like your typical herbal supplement, but it does come with all the issues common to the supplement industry. Namely, it hasn't withstood the test of clinical trials to demonstrate safety and efficacy.  And that causes problems.   Problems like not knowing how much of the ingredient is in the supplement, or how much of other ingredients for that matter. Or wht kind of side effects might be evident if it were subjected to randomized placebo-controlled trials.   But another problem is that it might actually offer a solution to a very big problem—opioid addiction But we don't know if it does because guess what? It hasn't been studied.   This week, 2 Docs Talk about Kratom and why the regulatory requirements (or absence thereof) on the supplement industry might be causing us to miss out on some real benefits.

Episode 125: Kratomic Explosion

With our apologies to and appreciation of Frances McDormand.  The opioid crisis is showing no signs of tapering off any time soon, so today, 2 Docs Talk about the cornerstone of opioid addiction treatment - medication assisted therapy or MAT.  We also (because we can't resist) talk about the irony of the very company who triggered the epidemic with their deceitful marketing practices now profiting from selling the treatment for that very problem.  Resources:  Previously, we disucssed the opioid epidemic in episode 12 - you can find it right here.

Episode 124: Treating Opioid Addiction

After a hiatus that lasted much longer than planned, we are back with our fall 2018 season of 2 Docs Talk, with look back on previous topic and an update on what's been going on since we first discussed them. We'll talk about the following episodes:   Hormone Supplementation and Menopause  Right to Try Legislation The Flu, the Flu Shot and the Future Cervical Cancer and the HPV Vaccine  Medicaid Expansion The Mumps   Other resources for this episode can be found here:  JAMA article on racial differences in vasomotor symptoms    Info on HPV vaccine expanded recommendations Mumps booster information

Ep 25: Cholesterol and Heart Disease: What We Don't Know

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