Our Guest Author is Louis Diehl, Professor of Medicine at the Duke University School of Medicine in Durham, North Carolina. Dr. Diehl will present patient cases which will help listeners to: Confirm the diagnosis and chronic lymphocytic leukemia (CLL) utilizing the major anatomic and biologic prognostic factors, formulate initial treatment criteria and select an initial treatment regimen for a patient with CLL, and finally select the second treatment regimen for patients who may be progression on/after initial FCR treatment.