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The climate isn’t just warming—it’s reorganizing the rules of biology. We explore how rising temperatures, deforestation, wildfire smoke, and thawing permafrost are reshaping the risk landscape for malaria parasites, heat-trained fungi, spillover-prone viruses, and resilient bacteria. From Kenyan highlands that became friendlier to Anopheles mosquitoes, to urban heat islands that may condition fungi to tolerate our body temperature, to the sobering lesson of Siberia’s anthrax outbreak after unusual warmth, we connect data points to the lived reality of health systems on the front lines.

We dive into malaria’s life cycle and why vector capacity accelerates in warmer, deforested microclimates. We examine fungal threats, including how wildfire smoke can disperse spores, and why limited antifungal options raise the stakes. On viruses, we unpack Ebola’s reservoir ecology, the role of habitat loss and food insecurity in human–animal interfaces, and how language and stigma can undermine outbreak response. Finally, we look at bacterial risks within permafrost feedback loops and across water and food systems, where floods, droughts, and soil microbiome shifts threaten safety and yields.

Throughout, we keep solutions in focus: protecting forests and wetlands, cutting fossil fuels and air pollution, building climate-smart surveillance and diagnostics, and communicating with dignity so communities participate in prevention. Climate action is infection prevention—and it starts now. If this conversation sparked new questions or ideas, subscribe, share with a friend, and leave a review to help more people find the show. What solutions can you enact in your life to face the rising threat?

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