In this episode of Clinical Trialblazers, host Alberto Grignolo sits down with Reenie McCarthy, the CEO of Mighty Therapeutics, formerly known as Stealth BioTherapeutics. Reenie shares her path from venture investor to biotech CEO and the years-long effort to develop and secure approval for a first-in-class therapy targeting mitochondrial dysfunction. She discusses the scientific, regulatory, and funding challenges of advancing a novel treatment through clinical development, as well as the critical role of patient advocacy and the lessons learned from setbacks that ultimately helped shape the company's success.

The conversation also explores the future of mitochondrial medicine and Mighty Therapeutics' mission to bring innovative treatments to patients with serious unmet needs.  

We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen.

Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi.

Clinical Trialblazers is back for Season Two. Host Alberto Grignolo speaks with Paul Garofolo, Co-Founder and CEO of Locus Biosciences, about the leadership mindset behind capital efficiency, resource prioritization, and disciplined execution. Drawing on Paul’s journey from global leadership roles at Patheon to founding a next-generation precision medicine company, this episode explores fundraising across market cycles, founder-friendly capital, strategic and government partnerships, and the science behind Locus’ bacteriophage-based platform aimed at tackling multidrug-resistant infections.

We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen.

Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi.

In this season finale of Clinical Trialblazers, host Alberto Grignolo reflects on key insights and themes from conversations with biotech leaders over the past year. From researchers to entrepreneurs to investors, Alberto spoke with a wide range of leaders in the biotech industry, each with a unique perspective on the evolving biotech landscape and advice for aspiring innovators. This episode is just a sampling of the many compelling stories and lessons shared in this remarkable first season. 

We hope you enjoyed this season of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen.

Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi. 

We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen.

Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi.

In this episode of Clinical Trialblazers, Alberto sits down with Dr. Geeta Vemuri, Founder and Managing Partner of Agent Capital. They discuss Dr. Vemuri’s journey into venture capital, offering valuable insights on what makes successful biotech companies and CEOs stand out. She also speaks about the critical balance between scientific innovation and strong management teams, the role of capital efficiency in building sustainable companies, the value of board membership, and what excites her about the future of biopharma.

We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen.

Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi.

In this episode of Clinical Trialblazers, host Alberto Grignolo sits down with Miquel Vila-Perello, Ph.D. co-founder and CEO of SpliceBio, a gene therapy company focused on treating Stargardt disease. They discuss Miquel's journey from academia to biotech, the challenges of fundraising, the importance of passion and resilience in drug development, and the future of gene therapy. Miquel shares insights on balancing rationality and passion, the differences between academic and industry research, and the significance of building trust with investors.

We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen.

Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi.

We hope you enjoyed this week’s episode of Clinical Trialblazers. Please take a moment to rate and review this podcast wherever you listen.

Special thanks to our production partner, Wonder Media Network. Our producer is Brittany Martinez, our editor is Gianna Palmer and our production assistant is Joia Putnoi.