Despite high uptake of the quadrivalent meningococcal ACWY vaccine among adolescents, significant protection gaps remain, particularly against serogroup B. That’s why Dr. Ruth Carrico joins us to examine key challenges in adolescent vaccine delivery and how newer pentavalent vaccines covering all five major meningococcal serogroups—A, C, W, Y, and B—can streamline protection, improve coverage, reduce missed doses, and support shared decision-making between providers, teens, and parents.