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Codeine

Trade Name

Paveral

Indication

Management of pain, diarrhea, cough suppressant

Action

Binds to opiate receptors in the CNS and alters perception of pain while producing a general depression of the CNS. This depression also causes a decrease in the cough reflex and GI motility.

Therapeutic Class

Allergy, cold, cough remedy, antitussive, opioid analgesic

Pharmacologic Class

Opioid agonist

Nursing Considerations

• May cause alterations in mentation, hypotension, constipation, nausea, vomiting • Assess BP, pulse, and respiratory rate prior to administration and frequently during administration • Use caution if patient is receiving MAO Inhibitors • Narcan (naloxone) is the antidote for opioid agonists