Timed with the recent update of the British Society of Gastroenterology coeliac guidelines, the discussion explores why coeliac disease remains frequently underdiagnosed, even in specialist care. Together, they unpack the latest evidence on serology-based diagnosis, optimal biopsy strategies, potential and seronegative coeliac disease, and when HLA testing is truly useful.

The episode also covers long-term follow-up, the role of repeat biopsies, ultra-short coeliac disease, and emerging non-dietary therapies — including the realistic prospects of a future “pizza pill”.