Kidney Kids

Cola-Colored Urine: Hematuria Clues and Glomerular Red Flags


Listen Later

Hematuria is a common reason for pediatric nephrology referral, but distinguishing glomerular from non-glomerular causes is the key to building the right differential. In this episode, we walk through a practical approach to pediatric hematuria, beginning with confirmation by urine microscopy and then using urine color, red blood cell morphology, proteinuria, blood pressure, and kidney function to guide the workup.Topics include gross versus microscopic hematuria, false-positive dipsticks, dysmorphic red blood cells, RBC casts, post-streptococcal glomerulonephritis, IgA nephropathy, Alport syndrome, thin basement membrane disease, urinary tract infection, hypercalciuria, nephrolithiasis, Wilms tumor, Nutcracker syndrome, and when to refer to pediatric nephrology.

Selected References:

  • Horváth O, Szabó AJ, Reusz GS. How to Define and Assess the Clinically Significant Causes of Hematuria in Childhood. Pediatric Nephrology. 2023.

  • Brown DD, Reidy KJ. Approach to the Child With Hematuria. Pediatric Clinics of North America. 2019.

  • Expert Panel on Pediatric Imaging; Dillman JR, Rigsby CK, et al. ACR Appropriateness Criteria: Hematuria-Child. Journal of the American College of Radiology. 2018.

  • Savige J, Lipska-Ziętkiewicz BS, Watson E, et al. Guidelines for Genetic Testing and Management of Alport Syndrome. Clinical Journal of the American Society of Nephrology. 2022.

Have feedback, corrections, or suggestions for future episodes? We'd love to hear from you at [email protected].

Disclaimer: Kidney Kids is an educational podcast for medical students, pediatric residents, pediatric nephrology fellows, advanced practice providers, and practicing clinicians. The conversations use AI-generated voices portraying fictional physicians. This content is intended for educational purposes only and should not replace clinical judgment, institutional protocols, or consultation with qualified healthcare professionals.

...more
View all episodesView all episodes
Download on the App Store

Kidney KidsBy Kidney Kids