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This week on Bench Boost on team spotlights mining analysis challenges on ICP-MS due to high total dissolved solids, aggressive digestions, and low-ppb targets requiring interference control. They review ICP-MS interference types, giving examples such as ArO on Fe, and ArCl on As. The team explains how collision cell (helium KED) is used to reduce polyatomics and how reaction cell gases are used for mass-shifting analytes or interferences. Finally, they discuss triple-quad ICP-MS principles for stronger mitigation and share method-planning tips: isotope tables, chloride/oxide checks, survey scans, dilution/argon dilution for TDS, matrix matching (including HCl), calibration choices, and internal standards.